Testosterone Replacement Therapy


 

Testosterone Treatments & Hormone Replacement for Men

 

Over the years, our doctors see excessively fatigued, stressed, mentally exhausted, and overweight patients. This is very normal Low Testosterone symptoms. A decrease in the T count may occur at any time, not just during late adulthood or old age. Heat, acute disease, inadequate diet, and a variety of other disorders may result in male hormone imbalances. Testosterone therapy can help you live an optimal life. It can change your lifestyle to restore your strength, quality of life, and overall health.

TRT Video

ARE YOU EXPERIENCING LOW
TESTOSTERONE SYMPTOMS?

 

If you have any of these symptoms, you may have low testosterone.


  • Depression

  • Mood Swings

  • Decreased Strength of Orgasm

  • Erection Issues (Reduction in girth and stiffness)

  • Anxiety

  • Decreased Mental Sharpness

  • Muscle and Joint Pain

  • Problems Sleeping

  • Loss of Strength

  • Decreased Muscle and Increased Body Fat

  • Chronic Fatigue

  • Memory Loss

  • Use of Narcotic Pain Medications (even 6 months can cause Low-T)

  • Decreased Sex Drive

  • Weight Gain

  • Hot Flashes (thought it only happened to women?)

  • Low Sperm Count and Infertility

 

LOW-T QUIZ

 

TESTOSTERONE REPLACEMENT THERAPY

 

Did you know your testosterone begins to decline at age 30?
In some individuals, it happens even earlier!

Testosterone is the most important sex hormone in the male body. It is responsible for producing typical male characteristics such as body and facial hair, genital maturation, and muscle development and strength. It also promotes motivation and competitiveness as well as sexual function, sex drive, and influences the production of sperm.

We know that some men’s bodies just don’t produce enough testosterone. This can result in uncomfortable and oftentimes distressing symptoms.

If this sounds like you, then you’re not alone. In fact, the American College of Cardiology (ACC) estimates that 13 million American men may be suffering from low testosterone, but only 4 percent are currently treated. The ACC also reported that TRT is considered safe.

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THINGS ALL MEN NEED TO KNOW WHEN CONSIDERING TRT

 

GUYS! Here's a question...

... Is the situation below all too familiar to you?

You are tired. Maybe even half-asleep reading this…

…you’re feeling down, if not downright depressed.

And that’s saying nothing of your stubborn waistline or the lack of activity between the sheets…

... What's worse, those symptoms don't seem to shift with a good night's sleep.

You’re not sure what this is, but your Dr. Google Advisor said something about testosterone or 20 other things… You sure are hesitant to find out. In fact, you’d rather just keep toughing it out anywhere else besides sitting in a doctor’s office! Remember that friend you had that was suffering from some of the same issues? Didn’t he have low testosterone? Surely that can’t be it! Guys are great at justifying things, actually almost anything for a long, long time. By reading this, at least you are starting to take a proactive approach rather than a reactive one.

LOW-TQUIZ

If the scenario sounds all too familiar, chances are you’re suffering from low testosterone.

If you are like most men whom we've encountered over the years, it can be hard to comprehend. Actually, you probably deal with the news like, well, like a man: by not dealing with it at all!

This is hardly surprising but remember, you are not alone. It can be hard to broach the subject of your masculinity. Testosterone is the hormone we associate with sex and manhood, after all. If you’re suffering from fatigue, depression, or sexual performance problems, does that make you less of a man? Absolutely NOT!

It means, things are changing, and they are not fun at all. Just like puberty isn’t much fun for the kids…or the parents, change is hard. You see, your testosterone levels will naturally decline throughout your late 20s, and into your 30s, 40s, and beyond. When these male hormones reach critical levels in conjunction with a poor diet, lack of exercise, or just generally neglecting your body, the signs and symptoms slowly settle in.

Initially, because those symptoms are so gradual, it’s quite easy to not really notice it happening. Then, you start to ignore them. You will justify the symptoms for some time and then because you’re stubborn (hey, all of us men are), you just simply accept the suffering.

But, the story continues further. You stay silent about it. And this causes even more (maybe the most) undue harm.

Thankfully, more men are recognizing all of the benefits of testosterone replacement therapy and telling others about it. So, if you are considering getting things evaluated or you are just not where to begin, we will discuss this next.

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So, You Are Considering TRT?
Here Are The 5 Things You Need To Know

More and more men are considering TRT. The treatment has been shown to deliver more energy, improve sex, and provides overall higher quality of life.

If you have been considering testosterone therapy, it’s understandable that you’d have some questions. This is where you will find other FAQs. But, before you start testosterone replacement therapy, here are 5 things you need to understand.

 

How Your Testosterone Replacement Therapy Works

Step 1 - Evaluation

Your first appointment involves a complete health evaluation consisting of a thorough history and a detailed lab analysis with one of our providers.

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Step 2 - Strategy

Once the comprehensive lab results have been received, along with your unique history, we will guide your journey for improvement of your Low-T

Learn More

Step 3 - Action

(TRT) Testosterone Replacement Therapy will contain weekly or monthly visits with injections.

Learn More

Step 4 - Observation & Enhancement

While on TRT, you will have continuous monitoring of your progress, undergo appropriate lab studies as needed, as well as other personalized lifestyle enhancement options to assist you in becoming Optimal!

Learn More

 

IT'S TIME TO GET OPTIMAL!

 

We understand these topics are difficult to discuss with anyone.

Remember, you are not alone and we will help you through this process. We understand there is a lot of information all throughout this website but we hope that by presenting this material, you have begun to realize that these horrible symptoms that you are experiencing can change. 

Now, the ball is in your court. You can decide on the next step. Continue suffering or talk with a professional. And get your life back.

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So, You Are Considering TRT?
Here Are The 5 Things You Need To Know

 

 

 

 

 
 

 
 
 

LOW-T QUIZ

 

FAQs
FREQUENTLY ASKED QUESTIONS

 
What is Testosterone?

Testosterone is a sex hormone that plays an important role in the body. In men, it’s thought to regulate sex drive (libido), bone mass, fat distribution, muscle mass and strength, and the production of red blood cells and sperm. A small amount of circulating testosterone is converted to estradiol, a form of estrogen Both men and women have this hormone. But in the male, there is 7 to 10 times more circulating in the body.

This results in male characteristics much more different than a female such as increased bone mass, how fat is distributed throughout the body, as well as increased muscle mass, strength as well as higher production of red blood cells. Of course, men also produce sperm. Testosterone works in unison with other hormones, to feed your energy levels, calibrate your moods, and trigger your desire for, and your ability to have, sex.

Low t levels (take the quiz – add low T quiz) can disrupt these processes and spoil your quality of life.


Over the years, our clinicians are seeing patients who are overly fatigued, depressed, physically weak, and overweight. These are very common symptoms of Low Testosterone. A drop in T count can occur at any time, not just in mid-life or during old age. Male hormone imbalances can be brought by stress, acute illness, poor nutrition, and a host of other conditions. Testosterone therapy is the jumpstart men can take advantage of to make important changes in lifestyle that will restore their vitality, quality of life, and health.


Is Testosterone Therapy in Men Harmful?

A Critical Review of a Recent Observational Study and Media Attention on Testosterone and Heart Attack Risk

After a recent article on testosterone use was published in the Journal of the American Medical Association (JAMA), there has been an opportunity for law firms to capitalize on the suggested correlation between testosterone use and increased heart attack risk.

However, the observational study behind the article suggesting such correlation has received significant criticism on the basis of flawed study designs and serious analysis errors. Dr. Neal Rouzier, BHRT pioneer and expert, has written a critical review of the study’s resulting article from JAMA and television advertisements for various law firms.

You might have been alarmed by the recent television commercials from law firms soliciting patients that have taken testosterone and suffered a heart attack. Unfortunately, these campaigns have been influenced by a recent negative observational study of weak power and poor design and that has also been severely criticized by many medical experts in urology and endocrinology.

In spite of the worrisome television hype, patients and doctors should not be led astray or fear using testosterone solely based on the hysteria created by attorneys.

In contrast to this recent negative study, there are over 40 years of well-designed, randomized controlled trials and observational studies that all support the safety and efficacy of testosterone administration (I have provided references to some of those trials and studies below).

The most recent negative study of concern, which reported an association between the use of testosterone therapy and increased risk of death and heart attacks, appeared in the Journal of the American Medical Association (JAMA). Regardless of the study’s criticism, legal zealots have latched on to the negative conclusions as a basis for lawsuits including anyone that might have suffered a heart attack while taking testosterone.


The negative conclusions from this study have also reached the media, making patients concerned about their testosterone prescriptions. Because patients are unaware of the research from more than 40 years of supportive trials and studies, these patients now question if they should discontinue their testosterone medication.

-Why the JAMA Study Should Be Ignored-

In spite of this fear that has been instilled in the public by certain attorney groups, the public does not have enough experience or information to make informed decisions concerning the use of testosterone. I wish to explain and elaborate on why this study should be ignored and that no one should stop taking testosterone or fear taking it.

Physicians should not cease prescribing testosterone and patients should not stop using testosterone based on this one weak study, the results of which goes against a plethora of data showing safety and efficacy. I base my therapy on a composite of many studies over several decades of research and not on one rogue study that, in the opinion of medical experts, should be discarded.

It helps to understand the difference between a randomized controlled study (RCTs) and an observational study. In an RCT, subjects are screened to remove those that have other medical problems or issues that might adversely influence the data and results. To simplify understanding of RCTs, there is a treated group and a placebo group that are specifically tested by eliminating any patients that may have risk factors that would skew any results.

Observational studies, on the other hand, are not as powerful, accurate, or reliable as RCTs. In observational studies, careful selection does not take place, and reports (which may or may not be RCTs) are selectively reviewed without any regard to avoiding biases and errors. Reviewers pick and choose from the studies without randomization or control from other influencing factors, which can add inaccuracy and bias to any study. There was significant inaccuracy and error in this recent JAMA study.

Gross Data Mismanagement Calls for Corrective Action A post by three professional medical societies, along with an international group of 130 scientists and physicians, has petitioned JAMA to retract this recent article (JAMA 2013; 310:1829-36).

In a letter addressed to JAMA editors, the newly formed Androgen Study Group cites “gross data mismanagement thereby rendering the article no longer credible.” The article was one of two studies that prompted the FDA to issue a safety bulletin on the use of testosterone products. However, this warning from the FDA is only an advisory as the FDA has cautioned both patients and physicians not to stop testosterone therapy based on just one study, particularly when this study’s design flaws incorrectly led to negative results.

This article has already undergone two published corrections.

The first was published in January due to misreporting of primary results. A second correction published in March revealed what the group called “major errors” in the article’s text and figures.

In other words, the statistical analysis utilized was inappropriate and other statistical methods actually show opposite results with beneficial connotations. Furthermore, the numbers used for the statistical analysis were different from the numbers published in their tables. The raw numbers in their tables actually proved protection against myocardial infarction (heart attack), not the increased risk that they published. It is not until their data is plugged into a complex analytical scheme that it shows harm, hence the insistence for JAMA to retract the article. The petition was signed by the International Society for Sexual Medicine, the Sexual Medicine Society of North America, and the International Society for the Study of the Aging Male, along with more than 125 scientists and physicians (of which I am one).

“This is an extraordinary event,” said Abraham Morgentaler, MD, of Harvard University who is chairman of the Androgen Study Group. “In my 25 years in academic medicine, I have never witnessed anything like this response to a journal article.”

He adds that the call for retraction of an article is exceedingly rare. “To have several professional societies and so many of the most accomplished experts in the field unite in this action indicates the seriousness of the article’s errors, and the magnitude of damage this article has caused to the public’s perception of testosterone therapy.”


What does the treatment cost?

A Critical Review of a Recent Observational Study and Media Attention on Testosterone and Heart Attack Risk

After a recent article on testosterone use was published in the Journal of the American Medical Association (JAMA), there has been an opportunity for law firms to capitalize on the suggested correlation between testosterone use and increased heart attack risk. However, the observational study behind the article suggesting such correlation has received significant criticism on the basis of flawed study designs and serious analysis errors. Dr. Neal Rouzier, BHRT pioneer and expert, has written a critical review of the study’s resulting article from JAMA and television advertisements for various law firms.

You might have been alarmed by the recent television commercials from law firms soliciting patients that have taken testosterone and suffered a heart attack. Unfortunately, these campaigns have been influenced by a recent negative observational study of weak power and poor design and that has also been severely criticized by many medical experts in urology and endocrinology.

In spite of the worrisome television hype, patients and doctors should not be led astray or fear using testosterone solely based on the hysteria created by attorneys.

In contrast to this recent negative study, there are over 40 years of well-designed, randomized controlled trials and observational studies that all support the safety and efficacy of testosterone administration (I have provided references to some of those trials and studies below). The most recent negative study of concern, which reported an association between the use of testosterone therapy and increased risk of death and heart attacks, appeared in the Journal of the American Medical Association (JAMA). Regardless of the study’s criticism, legal zealots have latched on to the negative conclusions as a basis for lawsuits including anyone that might have suffered a heart attack while taking testosterone.

The negative conclusions from this study have also reached the media, making patients concerned about their testosterone prescriptions. Because patients are unaware of the research from more than 40 years of supportive trials and studies, these patients now question if they should discontinue their testosterone medication.


If I am on TRT and transferring care to Optimal Men's Center, do I need to complete labs all over again?

No. We understand that things change. If you currently are on TRT or were in the last 6 months, you can be seen and usually not have to have any new labs drawn. However, you will need to be seen for a new patient visit but this appointment is usually scheduled quickly so you do not have a further lapse in treatment.


Will my insurance cover the bills?

Optimal Men’s Center is a concierge-style clinic, without the concierge price tag! As stated above, we do take most insurances and typically you will just have a copay for the in-office injections. However, with the numerous forms of insurance policies out there, we can discuss things in person. If you have a deductible and high deductible plans, we can provide a bill that can be submitted and, based on your policy and the services you receive, you may see some reimbursement. Please understand that any reimbursement for treatment is between you and your insurance provider.

We will only treat patients after testing confirms there is a need for medical treatment. If levels are not on the lower ranges, if there is a medical issue that precludes treatment, or a person is seeking medical treatment for non-medical reasons, Optimal Men’s Center will not be able to treat the individual.

Remember that by avoiding insurance directly allows us to provide cutting edge, highly effective treatment with no strings attached.


Does seeing one of your clinicians automatically qualify me for treatment?

We will only treat patients after testing confirms there is a need for medical treatment. If levels are not on the lower ranges, if there is a medical issue that precludes treatment, or a person is seeking medical treatment for non-medical reasons, Optimal Men’s Center will not be able to treat the individual.


Should I expect side effects of Hormone Replacement Therapy?

Properly prescribed, finely-tuned treatment eliminates side effects for the majority of men. Potential side effects occur when the dosing of one or more components of treatment is sub-optimal or excessive. When side effects do occur they are typically mild and can usually be easily addressed with a slight adjustment to the treatment plan. Most patients that have side effects keep it to themselves. Remember that we are available at any time you have questions.

Some side effects can include:
Increased body temperature (think higher metabolism too!)
Acne – most commonly on shoulders
Irritability or agitation


I heard that “free” testosterone levels are more important than total testosterone. Is this true?

Yes. But, there is much more to evaluating a man’s hormone status than a simple total testosterone reading. Some men have a fair amount of testosterone but not enough of it is actually bio-available for the body to use. Assessing the “free” or “bioavailable” portion of the hormone is critical, and in our experience, rarely evaluated by doctors who do not specialize in BHRT.


If I decide I want to undergo hormone treatment, do I need to inject myself with a needle?

Not necessarily. Most of our patients come into the office for injections because it is usually much cheaper due to insurance payments. Some patients do elect to self-administer subcutaneous (very shallow) or intramuscular (slightly deeper) injections with small-gauge needles…but there are other alternatives. Some patients choose to use creams that absorb through the skin. Some patients are good candidates to have small “pellets” implanted into an area of fatty tissue – an alternative to injections and creams.


Is this an ongoing or lifetime treatment?

Many providers of TRT will tell you that…it depends, knowing that they want you on this for life so they can continue to make money treating you. However, there is evidence to the contrary.

Typically, TRT is administered in cycles with other medications that are used to help keep the natural (endogenous) production of testosterone at its maximum level. When TRT is delivered this way along with accompanying medications it allows the body a chance to rehabilitate itself and naturally increase its own (endogenous) T production. Also, it is absolutely imperative that TRT is used in combination with a proper diet and exercise plan. Research has shown that excess belly fat is a major culprit for low T levels; since it triggers estrogen production as well as insulin resistance which can drastically hurt the body’s levels of endogenous T production.

Several studies have shown that TRT promotes fat loss and encourages muscle building, thanks to its powerful impact on muscle protein synthesis. Often when men with Low T lose significant body fat and gain muscle mass, the testicles will begin to produce more of their own T once again. If other lifestyle factors are reversed such as continued improvement in sleep quality and normalized sleep schedule, continued/persistent weight loss maintenance, reduction in stress, and discontinuation of any medications [such as narcotics or certain medications like for seizures (not usually recommended on the second)] are also quite helpful. IF these modifications to lifestyle and weight loss are tenaciously followed, lifelong TRT may not be necessary.

There is no one-size-fits-all solution for those men with low testosterone, but our team of clinicians will work with each and every patient on an individual basis to assist in establishing a regimen of bio-identical hormone replacement therapy that is right for them.


Are there any risks associated with TRT?

As with many medical interventions, particularly those requiring prescription medications, there are risks. Hormone replacement is a sophisticated medical intervention and requires expertise to perform both effectively and safely. Optimal Men’s Center urges anyone considering hormone treatment to seek an expert trained properly in Bio-identical Hormone Replacement Therapy (BHRT). If you are not sure, ask. This is not a game to be played with your body or your health.

Many doctors shy away from HRT. Some even discourage it in general. From our experience, this is a consequence of a lack of knowledge combined with fear of the unknown.

A clinician with proper training, repetition, and ultimately expertise with this specific intervention – gained through thousands of patient contacts and years of follow-up – can confidently offer effective, safe HRT. This is what you will find with the clinicians at Optimal Men’s Center.


What about risks involving cardiovascular or prostate health?

The risk with prostate health concerns men are those with preexisting prostate cancer. For those patients, there is some concern that testosterone may encourage the growth of abnormal cells, although a direct correlation has not been firmly established. See this study regarding TRT for patients who actually had prostate cancer and had decreased PSA levels.

As for cardiovascular (CV) concerns, with appropriate dosing and consistent monitoring, there are both short and long-term benefits as it pertains to such CV events like heart attacks and strokes. Many studies show these advantages. However, we do understand that every patient is unique and needs close observation.


Isn’t there something I can do to permanently address my low T or ED situation?

Proper nutrition and exercise are absolutely essential for optimal health. Sometimes specific nutrients or other supplemental measures can make a big difference. However, there are often greater obstacles that will bring guys in for a visit. We will make a thorough assessment and then discuss the options so each patient can make an informed decision about how they would like to address their health needs. There are numerous supplements that can assist men in their drive for feeling Optimal.

However, when it comes to supplements that are supposed to increase a man’s testosterone, we have yet to see even one that works more than a few months (we have done labs to disprove the manufacturer claims). There are a few that can increase mild conversion to Free Testosterone but if you have low Total Testosterone to start off with, you will not gain much Free T to be of any significance. Unfortunately, men who have Low-T are notoriously targeted by supplement companies with promises that are just too good to be true.


Is hormone therapy like taking steroids?

Our patients’ hormone deficiencies are treated with bio-identical hormones that are engineered to work with how the body functions. We treat our patients to bring their hormone levels back to where they are safely determined best. Men who abuse steroids are people that will sacrifice safety in order to develop excessive hormone levels, which is a very dangerous way to achieve an increase in muscle mass. This is not sustainable and will cause significant health issues down the road.


Viagra and Cialis did not really help with erectile function. Is all hope lost?

Not at all. Such oral medications like Viagra and Cialis work great for many men, but they are not effective for others. Sometimes just changing the route of administration that we use such as sublingual (under the tongue (troches or dissolvable) meds or Trimix (microinjections), we are able to find satisfying solutions for over 90% of our patients.


Higher Testosterone Levels Associated with Better Cardiovascular Outcomes

Dr. Morgentaler went on to say, “Lost in the media frenzy that followed this article’s publication is the fact that substantial evidence accumulated over 30 years has repeatedly shown that higher testosterone levels are associated with better cardiovascular outcomes. In the interests of medical science and the public good, JAMA should do the right thing and retract the article.”

“Many of my patients stopped taking testosterone because of the JAMA article, even those who had experienced substantial benefits. And now we find out it was all based on nothing but sloppy science. We are talking about real consequences on individuals’ health and quality of life,” states Dr. Morgentaler. The Androgen Study Group says it is dedicated to the education and accurate reporting on the science of testosterone deficiency and treatment in men. It was organized specifically to respond to the “recent unwarranted, unscientific attacks” on testosterone therapy in medical and public media.


THE HORMONES BELOW ARE TANTAMOUNT TO OUR TREATMENT at OMC. THE MOST IMPORTANT HORMONES THAT NEED TO BE STABILIZED/NORMALIZED for patients are:

TESTOSTERONE
ESTRADIOL
THYROID
CORTISOL
DHEA
BLOOD SUGAR HORMONES
If Abnormal FBS (fasting blood sugar), further testing may include:
A1C (3 Month Blood Sugar Average) and/or
FASTING INSULIN LEVEL


REFERENCES

Baker B. Testosterone patch increases BMD in elderly men. Family Practice News. 1999 Oct 15.
Barrett-Connor EL. Testosterone and risk factors for cardiovascular disease in men. Diabete Metab. 1995 Jun;21(3):156-161.
Barrett-Connor E, Khaw KT, Yen SS. A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. N Engl J Med. 1986 Dec 11;315(24):1519-1524.
Boshert S. Concerns about testosterone replacement safety evolve. Family Practice News. 2004 November 1.
Carter HB, Pearson JD, Metter EJ, et al. Longitudinal evaluation of serum androgen levels in men with and without prostate cancer. Prostate. 1995 Jul;27(1):25-31.
Cookson MS, Smith J. PSA Testing: Update on Diagnostic Tools. Consultant. 2000 April 1.
English KM, Steeds RP, Jones TH, et al. Low-dose transdermal testosterone therapy improves angina threshold in men with chronic stable angina: A randomized, double-blind, placebo-controlled study. Circulation. 2000 Oct 17;102(16):1906-1911.
Faloon W. A new, independent risk factor for heart disease. 2004 Aug. http://www.lef.org/magazine/mag2004/aug2004_awsi_01.htm. Accessed January 2012.
Fukui M, Kitagawa Y, Nakamura N, et al. Association between serum testosterone concentration and carotid atherosclerosis in men with type 2 diabetes. Diabetes Care. 2003 Jun;26(6):1869-1873.
Ginsberg TB, Cavalieri TAPg 9 to 12 – Gaby, A. R. DHEA: The hormone that does it all. Holistic Medicine. 1993 Spring:19-23.
Gordon GB, Bush DE, Weisman HF. Reduction of atherosclerosis by administration of dehydroepiandrosterone. A study in the hypercholesterolemic New Zealand white rabbit with aortic intimal injury. J Clin Invest. 1988 Aug;82(2):712-720.
Hak AE, Witteman JC, de Jong FH, et al. Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab. 2002 Aug;87(8):3632-3639.
Herrington DM. Dehydroepiandrosterone and coronary atherosclerosis. Ann N Y Acad Sci. 1995 Dec 29;774:271-280.
Heufelder AE, Saad F, Bunck MC, Gooren L. Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone. J Androl. 2009 Nov-Dec;30(6):726-733.
Rhoden EL, Morgentaler A. Medical Progress: Risks of Testosterone-Replacement Therapy and Recommendations for Monitoring. N Engl J Med. 2004 Jan; 350:482-492.
Labrie F, Diamond P, Cusan L, et al. Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab. 1997 Oct;82(10):3498-3505. Androgen deficiency in the aging male: The beginning, the middle, and the ongoing. Clinical Geriatrics. 2008 April;16(4):25–28.
Maggio M, Lauretani F, Ceda GP, et al. Relationship between low levels of anabolic hormones and 6-year mortality in older men: the aging in the Chianti Area (InCHIANTI) study. Arch Intern Med. 2007 Nov 12;167(20):2249-54.
Malkin CJ, Pugh PJ, Morris PD, et al. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life. Heart. 2004 Aug;90(8):871-6.
Malkin CJ, Pugh PJ, Jones RD, et al. The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab. 2004 Jul;89(7):3313-3318.
Moffat SD, Zonderman AB, Metter EJ, et al. Free testosterone and risk for Alzheimer disease in older men. Neurology. 2004 Jan 27;62(2):188-193.
Morales AJ, Nolan JJ, Nelson JC, Yen SS. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab. 1994 Jun;78(6):1360-1367.
Muller M, Aleman A, Grobbee DE, et al. Endogenous sex hormone levels and cognitive function in aging men: is there an optimal level? Neurology. 2005 Mar 8;64(5):866-871.
Jancin B. Testosterone replacement curbs inflammatory cytokines. Clinical Psychiatry News. 2004 May
Khaw KT, Dowsett M, Folkerd E, et al. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Circulation. 2007 Dec 4;116(23):2694-701.
Selvin E, Feinleib M, Zhang L, et al. Androgens and diabetes in men: results from the Third National Health and Nutrition Examina tion Survey (NHANES III). Diabetes Care. 2007 Feb;30(2):234-238.
Shores MM, Matsumoto AM, Sloan KL, Kivlahan DR. Low serum testosterone and mortality in male veterans. Arch Intern Med. 2006 Aug 14-28;166(15):1660-1665.
Villareal DT, Holloszy JO. Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. JAMA. 2004 Nov 10;292(18):2243-2248.
Van Vollenhoven RF, Morabito LM, Engleman EG, McGuire JL. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol. 1998 Feb;25(2):285-289.
Winters SJ. Current status of testosterone replacement therapy in men. Arch Fam Med. 1999 May-Jun;8(3):257-263.Winters SJ.
Wolkowitz OM, Reus VI, Roberts E, et al. Dehydroepiandrosterone (DHEA) treatment of depression. Biol Psychiatry. 1997 Feb 1;41(3):311-318


 

*Certain labs are excluded but we will give you special rates (for example: Fasting IGF-1 level w Z-score is over $600 at LabCorp but our price is $78 – as of 2019)

 

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